Validation of the familial chylomicronaemia syndrome (FCS) score in an ethnically diverse cohort from UK FCS registry: Implications for diagnosis and differentiation from multifactorial chylomicronaemia syndrome (MCS)

Bilal Bashira,b ∙ See Kwoka ∙ Anthony S. Wierzbickic ∙ Alan Jonesd ∙ Charlotte Dawsone ∙ Paul Downief,g ∙ Fiona Jenkinsonh∙ Hannah Delaneyi ∙ Michael Mansfieldj ∙ Dev Dattak ∙ Yee Teohl ∙ Paul Hamiltonm,n ∙ Natalie Forrestero ∙ Dawn O’Sullivanp ∙ Maryam Ferdousia ∙ Paul N. Durringtona ∙ Alaa AbdelRazikq ∙ Antonio Gallor,s ∙ Philippe Moulint ∙ Handrean Sorana,b Abstract Background and aims Prognosis and management differ between familial chylomicronaemia syndrome (FCS), a rare autosomal recessive disorder, and multifactorial chylomicronaemia syndrome (MCS) or severe mixed hyperlipidaemia. A clinical scoring tool to differentiate these conditions has been devised but not been validated in other populations. The objective of this study was to…

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Current Dietary Practice in the Management of Adults with Familial Chylomicronaemia Syndrome

A UK Expert Panel Opinion Piece Introduction Familial chylomicronaemia syndrome (FCS) is a rare autosomal recessive disorder with an estimated prevalence of 1–2 per million, which equates to 55–110 people in England.1, 2 FCS is characterised by severe fasting hypertriglyceridaemia (HTG), defined as triglyceride (TG) concentrations >10 mmol/L (885 mg/dL) by the European Atherosclerosis Society Consensus…

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Rare Disease Day 2025

Rare Disease Day 2025 is Friday 28 February. Add your support to everyone who is affected by a rare disease. And meet our ultra-rare zebra!

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FCS Awareness Day 2023

FCS Awareness Day is on Friday 3rd November 2023. We’re asking you to take the FCS 10g Challenge and to nominate others to join you, and to share your experiences to raise awareness.

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FCS in Children: Webinar

Watch our webinar FCS in Children
Recorded on Wednesday 26th April 2023

Join us to hear our four speakers to learn more about managing FCS in childhood.

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New role for our Chair

We’re delighted to announce that our Chair, Jill Prawer, will be joining FH Patients Europe as Rare Disease Project Manager on Rare Disease Day 2023!  In her role Jill will be responsible for patient advocacy and patient support projects focusing on rare familial lipid conditions – HoFH and FCS. “I’m really excited to be working…

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